A NETWORK-BASED APPROACH TO INTEGRATE NUTRIENT MICROENVIRONMENT IN THE PREDICTION OF SYNTHETIC LETHALITY IN CANCER METABOLISM.

A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism.

Synthetic Lethality (SL) is currently defined as a type of genetic interaction in which the loss of function of either of two genes individually has limited effect in Lounge Socks cell viability but inactivation of both genes simultaneously leads to cell death.Given the profound genomic aberrations acquired by tumor cells, which can be systematical

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A rare case of a concomitant inguinal and obturator hernia and their laparoscopic transabdominal repair: A case report

An obturator hernia remains a rare occurrence and accounts for less than 1% of all abdominal wall hernias.To have a concomitant presentation with a direct inguinal hernia makes this an extremely rare case report.This patient did not fit the usual epidemiological profile of an elderly female with small intestinal obstruction.This was a male patient

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